Speaking of desktop or wall mounted, I found this link to an easy to follow article on a wall mounted frame. Wires go in your wall at the frame and come out near the floor.
This is the only way I would mount a frame on the wall, wires must be hidden. Keep in mind that this is a fairly permanent solution; if you move it, there will be a nice gaping whole right at eye level. It’s not that hard to cover it up with another frame, but, still, something to think about.
The writer used Irfanview, a great simple photo editor and slideshow software, to run the photo slideshow. He also remotes to the laptop using the built in windows tool and a shared folder over his network.
Oh yea, the frame itself is obviously not a self contained computer. It’s actually just an older monitor mounted to a frame. This helps tremendously with heat since there is no motherboard or CPU. This also makes repairs or upgrades to the PC less of a hassle since you don’t have to take down and open up your frame.
Very clean install and a seamless software solution, great solution overall.
Wall Mounted DIY Digital Photo Frame | Shuttertalk.